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Leiden University Medical Center (LUMC) uses Quest Spectrum in ground breaking long tumor surgery

24-04-2018

A team from the cardiothorax surgery department in in the LUMC and the Centre for Human Drug Research removed a long tumor that was detected by using fluorescence. This was the first time in Europe that this technique was applied on long tumor patients.

The fluorescent marker is developed in collaboration with the American company On Target and was previously successfully applied by the LUMC on patients suffering from ovarian cancer. This tumor marker, OTL 38, that is injected preoperatively, will bind to the tumor cells and can be detected using the Quest Spectrum. Using this system the surgeon is able to visualize the tumor together with the possibly infected lymph nodes. Additionally the targeted marker allows him to better identify the tumor margins, this will potentially lead to complete resection of the tumor tissue together with the retention of healthy tissue.

This text is partially derived and translated from the LUMC press release (in Dutch) that can be found here or by clicking the content of the LUMC LinkedIn post shown on this page.
The press release was also picked up by Noordhollands Dagblad, Sleutelstad and Leiden University.

Quest Medical Imaging part of consortium grant for evaluation of new fluorescent tracer

09-01-2018

Dr. Vahrmeijer from the Leids Universitair Medisch Centrum (LUMC) has obtained a Consortium Grant to improve visualization tools for rectal cancer. Intraoperatively, tumor tissues are visually indistinguishable from healthy tissues  by the naked eye. Therefore, Vahrmeijer and his colleagues have started a collaboration with Surgimab and Quest Medical Imaging to improve the contrast with help of fluorescent imaging. Surgimab delivers a compound that can label rectal cancer cells and Quest Medical Imaging delivers the Quest Spectrum to visualize the compound together with the natural color image. This collaboration can result in new technology that allows more accurate surgery with decreased chance of resurrection of tumor tissue.

If you want to know more about this Grant, please read LUMC its official press release.

Quest Medical Imaging part of 29 mln EU Excel grant EXIST

01-03-2017

Quest Med­ical Imag­ing BV has been rewarded an EU Excel grant with a total val­lue of 29 mln euro’s. The three year pro­gram has started on May 1st 2017 this year.

EXIST addresses soci­etal needs in the auto­mo­tive, agri­cul­ture, secu­rity, pro­fes­sional broad­cast and health­care mar­kets. These needs will be addressed by improv­ing the per­for­mance of advanced image cap­tur­ing sys­tems at the dif­fer­ent lev­els of an imag­ing system:

  • Image sen­sors;
  • Video pro­cess­ing inside cam­era systems;

Improved image qual­ity will allow for the extrac­tion of more detailed infor­ma­tion and a wider range of applic­a­bil­ity such as.

  • Secu­rity,
  • Med­ical,
  • Pro­fes­sional Broad­cast Media, and
  • Auto­mo­tive applications.

New tech­nolo­gies will be devel­oped at the imager process tech­nol­ogy level and the imag­ing and vision sys­tem design. Their rel­e­vance will be demon­strated in a num­ber of applications.

The devel­oped tech­nolo­gies will enable new vision sys­tems answer­ing soci­etal needs,

To min­i­mize poten­tial com­pli­ca­tions of open surgery, as a diag­nos­tic and inter­ven­tional pro­ce­dure, the cur­rent health­care ten­dency is to move towards robotic image-guided laparo­scopic surgery. How­ever, when spa­tial per­cep­tion from direct sight and hap­tic feed­back from direct touch are lack­ing, iden­ti­fi­ca­tion of crit­i­cal tis­sues becomes extremely chal­leng­ing. This can be tack­led by e.g., increas­ing field-of-view and pro­vid­ing image enhance­ment and clas­si­fi­ca­tion of crit­i­cal tissues.

For exam­ple, tumour resec­tion region is par­tic­u­larly chal­leng­ing for the human eye and it often needs to be eval­u­ated after­wards with high prob­a­bil­ity to either exten­sive and dam­ag­ing resec­tion or reop­er­a­tion. There­fore, a reli­able tool to enhance the con­trast of between crit­i­cal tis­sues is desir­able for improved results of laparo­scopic pro­ce­dures. Explor­ing opti­cal spec­troscopy tech­niques might offer a roadmap towards such a tool, as all tis­sue types dif­fer in their spec­tral fin­ger print. Using advanced and multi-modal laparoscopy, by adding a HD hyper­spec­tral imag­ing on top of cur­rent RGB video and by extend­ing data pro­cess­ing to sup­port advanced deci­sion sup­port, will add enor­mously to dis­ease out­come and patient well­be­ing and cut­ting costs at the same time.

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