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Promising applications

We con­sider the poten­tial ben­e­fit of using the Quest Spectrum™ Platform in com­bi­na­tion with ICG or Meth­yl­ene Blue in the fol­low­ing appli­ca­tion the most promis­ing:

Sen­tinel Lymph Node Detec­tion with ICG has the poten­tial ben­e­fit of eas­ier find­ing the lymph nodes, need­ing smaller inci­sions and speed­ing up the procedure.All axil­lary SLNs detected by γ (gamma) trac­ing are also detected with NIR flu­o­res­cence imag­ing. In the fol­low­ing can­cer­types Sen­tinel Lymph Node Detec­tion with ICG seems to have added vallue:


Visu­al­iza­tion of:

  • Col­orec­tal liver metas­tases: (open or laparo­scopic) the main poten­tial ben­e­fit is that in 12,5% of patients addi­tional small lesions are found by means of NIR flu­o­res­cent imag­ing which where oth­er­wise undetectable.
  • Parathy­roid ade­no­mas: The wide vari­abil­ity of the anatom­i­cal loca­tion, shape, and num­ber of parathy­roid glands makes suc­cess­ful parathy­roid surgery chal­leng­ing. The suc­cess rate is high butin­tra­op­er­a­tive imag­ing tools could aid in the local­iza­tion of dif­fi­cult local­ized parathy­roid ade­noma and in addi­tion pos­si­bly reduce time of surgery.


  • Ureters: (open or laparo­scopic) Iatro­genic ureteral injury is a rare, but can result in severe com­pli­ca­tions. Iden­ti­fi­ca­tion of the ureters can be chal­leng­ing in the set­ting of pelvic tumors, inflam­ma­tion or after radi­a­tion to the pelvic area Early iden­ti­fi­ca­tion of ureteral dam­age per­mits direct repair and is of para­mount impor­tance to reduce mor­bid­ity and preser­va­tion of renal function.With Meth­yl­ene blue the ureters can be visu­al­ized and identified.

Per­fu­sion of:

Colon:(open or laparo­scopic) Anas­to­motic leak­age is the most dreaded of all com­pli­ca­tion in col­orec­tal (can­cer) surgery. Research shows that a sig­nif­i­cantly reduced rate of revi­sion (about 60% and more) is possible when surgery is done in com­bi­na­tion with NIR flu­o­res­cence imaging.

Esophagectomy and Gastric graft: (open or laparo­scopic) with removal of the esoph­a­gus replacing it with a gastric graft, it is hard to judge how well the upper stomach region is per­fused. Judg­ing the per­fu­sion may lead to dif­fer­ent sur­gi­cal out­comes low­er­ing the rate of leakage.